Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Hebert LE, Weuve J, Scherr PA, & Evans DA (2013). Dementia and Geriatric Cognitive Disorders, 45(1–2), 49–55. Healthcare professionals can interpret the level of impairment based on a score out. Incremental Validity of Montreal Cognitive Assessment Index Scores in Mild Cognitive Impairment and Alzheimer Disease. The Montreal Cognitive Assessment (MoCA) test can detect mild cognitive impairment or early signs of dementia. Goldstein FC, Milloy A, & Loring DW (2018). The optimal cutoff score for screening mild cognitive impairment (MCI) in older adults has been widely explored in applying the Montreal Cognitive Assessment (MoCA), which is a tool designed exclusively for screening MCI in older adults. Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia. Gefen T, Gasho K, Rademaker A, Lalehzari M, Weintraub S, Rogalski E, … Mesulam MM (2012). Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, … International Psychogeriatric Association Expert Conference on mild cognitive, i. Approach to atypical Alzheimer’s disease and case studies of the major subtypes. MoCA Index scores can help differentiate among distinct cognitive syndromes, suggesting it may be a useful brief screening tool to detect domain-specific cognitive impairment.Īlzheimer’s disease Assessment Cognition Dementias Neurodegeneration Primary progressive aphasia.ĭickerson BC, McGinnis SM, Xia C, Price BH, Atri A, Murray ME, … Wolk DA (2017). Multivariate logistic regression analysis showed that the individual effects of Memory (p =. 001), whereas Language and Attention Index scores were lowest in the PPA group (p <. However, in accordance with salient clinical features commonly observed in DAT versus PPA, Memory and Orientation Index scores were lowest in the DAT group (p <. 001) but did not differ between DAT and PPA groups. The mean MoCA total score was significantly higher in controls compared to both patient groups (p <. A logistic regression model was implemented to observe individual likelihood of group affiliation based on MoCA Index scores. A one-way analysis of covariance adjusted for age was used to compare MoCA scores among groups. This study compared MoCA Index scores between amnestic dementia of the Alzheimer's type (DAT) and primary progressive aphasia (PPA), a language-based dementia.īaseline MoCA data were analyzed from 33 DAT, 37 PPA, and 83 cognitively normal individuals enrolled in the Clinical Core of the Northwestern Alzheimer's Disease Center. 34,38 Using the standard threshold of >1 SD below the mean in 2 domains in the gold standard battery, MoCA showed higher sensitivity than MMSE using a cut-off value of 24. the thresholds to define cognitive impairment in the gold standard. It is unclear whether these MoCA scores can differentiate between distinct clinical dementia syndromes. The Montreal Cognitive Assessment (MoCA). The MoCA generates a total score and six domain-specific index scores: (1) Memory, (2) Executive Functioning, (3) Attention, (4) Language, (5) Visuospatial, and (6) Orientation. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.The Montreal Cognitive Assessment (MoCA) is a popular and simple-to-administer screening instrument to detect cognitive impairment. MCI as an entity is evolving and somewhat controversial. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively). In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD. Ninety-four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini-Mental State Examination (MMSE) score > or =17), and 90 healthy elderly controls (NC). To develop a 10-minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first-line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia.Ī community clinic and an academic center.
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